Antimastitic for drying treatment
Each 5 mL syringe tube contains:
Rifaximin ………………… 0.100 g
Excipients q.s.p …………….. 5 mL
- FATROXIMIN®, intramammary ointment is a preparation based on Rifaximin, a new antibiotic obtained by original synthesis, belonging to the Rifamycin family.
The particular chemical structure has given the molecule such chemical-physical characteristics that it has a pharmacokinetic that is completely different from the other rifamycins currently on the market.
The studies carried out reveal a practically null passage through the intramammary epithelium, allowing optimal availability of Rifaximin at the level of the fourth treated.
FATROXIMIN®, intramammary ointment has a high antibacterial activity of the bactericidal type against Gram positive microorganisms (Streptococcus spp., Staphylococcus spp., Corynebacterium spp.) And Gram negative ones (E. coli).
It acts on the most frequent microbial species in the udder.
FATROXIMIN®, intramammary ointment, is indicated in the drying of the cow for the therapy of existing subclinical mastitis, the prevention of a possible infection during the dry period and the prevention of acute postpartum mastitis, produced by Gram positive microorganisms (Streptococcus spp. , Staphylococcus spp., Corynebacterium spp.) And Gram negative (E. coli).
It acts on the most frequent microbial species in the udder sensitive to Rifaximin, such as: Streptococcus agalatiae, Streptococcus dysgalactiae, Streptococcus uberis, Streptococcus faecalis, Staphylococcus aureus (including the penicillin-resistant strains) and Staphymidis epidermis.
Field tests have shown:
- A high therapeutic activity, with bacteriological negativization of the rooms subjected to treatment and previously found infected due to Streptococcus agalatiae, Streptococcus dysgalactiae, Streptococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, with some penicillin resistant strains.
- A consequent preventive action, especially in secretory disorders of the breasts, that is, in those pathophysiological situations characterized by a high cellular content with the absence of pathological microorganisms in the milk.
ROUTE OD ADMINISTRATION AND DOSAGE
Intramammary route of administration
- Administer a 5 mL syringe tube of FATROXIMIN®, intramammary ointment, (equivalent to 100 mg of Rifaximin) per breast quarter, after the last milking, prior to drying.
- Milk the quarter thoroughly and after disinfecting the nipple orifice, then apply FATROXIMIN®, intramammary ointment, introducing the cannula and injecting the entire contents of the syringe.
- Subsequently, the nipple should be massaged from the bottom up to spread the product throughout the room.
- Do not administer in animals with hypersensitivity to Rifaximin.
- Do not administer in lactating cows.
- Do not administer to cows with clinical mastitis.